[Distribution of 5-fluorouracil between lymphocytes and blood plasma].
In: Ukrains'kyi biokhimichnyi zhurnal (1999 ), Jg. 85 (2013-07-01), Heft 4, S. 94-7
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Zugriff:
In blood plasma of 8 healthy volunteers with resuspended lymphocytes incubated with 5-fluorouracil (5-FU) the drug distribution between cells and liquid was assessed by means of HPLC. Rapid accumulation of 5-FU in lymphocytes was proved (the drug concentration on the 3-rd minute is 2.5-fold higher than in plasma) as well as the absence of temporal changes of 5-FU content both in lymphocytes and blood plasma during 30 minutes of experiment.
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[Distribution of 5-fluorouracil between lymphocytes and blood plasma].
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Autor/in / Beteiligte Person: | Stashkevich, MA ; Khomutov, EV ; Shatova, OP ; IuV, Dumanskiĭ ; Zinkovich, II |
Zeitschrift: | Ukrains'kyi biokhimichnyi zhurnal (1999 ), Jg. 85 (2013-07-01), Heft 4, S. 94-7 |
Veröffentlichung: | Kyïv : Nat︠s︡ionalʹna akademii︠a︡ nauk Ukraïny, Instytut biokhimiï im. O.V. Palladina, 1999-2013., 2013 |
Medientyp: | academicJournal |
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