URBAN AQUATIC ECOSYSTEMS AS A FACTOR OF THE SPREAD OF ANTIBIOTIC RESISTANT MICROORGANISMS AND RESISTANCE GENES.

In this work, studies have been conducted to detect antibiotic resistance microorganisms and resistance genes in the natural waters of the Uzh River, which flows in the Carpathian region (Ukraine) and flows into the Laborec River in the territory of Slovakia. Among the most common microorganisms of the Uzh River, there has been a high level of resistance to tetracyclines, β-lactams, and antibiotics of the last line of defence (carbapenems, fourth-generation fluoroquinolones). The results of molecular genetic analysis indicate the presence of resistance genes bla tet-M, bla CTX-M, bla TEM, and bla KPC in microorganisms of the Enterobacteriaceae family. [ABSTRACT FROM AUTHOR]

Die vorliegende Arbeit befasst sich mit den Ergebnissen von Untersuchungen über Nachweise Antibiotika resistenter Mikroorganismen und resistenter Gene in den natürlichen Gewässern des Uzh-Flusses, in der Karpatenregion der Ukraine entspringt und auf dem Gebiet der Slowakei in den Laborec-Fluss mündet. Unter den häufigsten nachgewiesenen Mikroorganismen des Uzh-Flusses fanden sich solche, deren Resistenz gegen Tetracycline, β-Lactame und Antibiotika der letzten Aktivitätslinie (Carbapeneme, Fluorchinolone der vierten Generation) hoch war. Die Ergebnisse der molekulargenetischen Analyse weisen auf das Vorkommen der resistenten Gene bla tet-M, bla CTX-M, bla TEM und bla KPC in Mikroorganismen der Familie der Enterobacteriaceae hin. [ABSTRACT FROM AUTHOR]

În această lucrare, au fost efectuate studii pentru a detecta microorganismele cu rezistență la antibiotice și genele de rezistență în apele naturale ale râului Uzh, care curge în regiunea Carpaților (Ucraina) și se varsă în râul Laborec pe teritoriul Slovaciei. Printre cele mai frecvente microorganisme ale râului Uzh, a existat un nivel ridicat de rezistență la tetracicline, β-lactame și antibiotice din ultima linie de apărare (carbapeneme, fluorochinolone de generația a patra). Rezultatele analizei genetice moleculare indică prezența genelor de rezistență bla tet-M, bla CTX-M, bla TEM și bla KPC în microorganisme din familia Enterobacteriaceae. [ABSTRACT FROM AUTHOR]

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