Simultaneous introduction of HIV type 1 subtype a and B viruses into injecting drug users in southern ukraine at the beginning of the epidemic in the former Soviet Union

NABATOV, Alexey A ; KRAVCHENKO, Olga N ; et al.

In: AIDS research and human retroviruses, Jg. 18 (2002), Heft 12, S. 891-895

academicJournal - print, 11 ref

The vast majority of HIV-1 strains from the epidemic in the former Soviet Union (FSU) belong to subtype A (IDU-A) and CRF03―AB (IDU-A/B), for which IDU-A is one of parental strains; no epidemic by another parental virus, belonging to subtype B (IDU-B), has yet been identified. To characterize viruses present during the early stage of the epidemic in southern Ukraine, where the first outbreaks in the FSU were registered, we obtained partial env and pol sequences from IDUs from Odessa and Nikolaev and compared them with viruses from other outbreaks. All viruses from Odessa belonged to the IDU-A type, which is in accord with previous studies. At the same time, we found that the outbreak in Nikolaev was caused by IDU-B viruses, indicating that this outbreak is the result of an independent virus introduction. Phylogenetic analysis of viruses from the FSU supported the epidemiological data suggesting that the HIV-1 epidemic in the FSU started in southern Ukraine.

Titel:	Simultaneous introduction of HIV type 1 subtype a and B viruses into injecting drug users in southern ukraine at the beginning of the epidemic in the former Soviet Union
Autor/in / Beteiligte Person:	NABATOV, Alexey A ; KRAVCHENKO, Olga N ; LYULCHUK, Maria G ; SHCHERBINSKAYA, Alla M ; LUKASHOV, Vladimir V
Link:	View record from PASCAL Archive
Zeitschrift:	AIDS research and human retroviruses, Jg. 18 (2002), Heft 12, S. 891-895
Veröffentlichung:	Larchmont, NY: Liebert, 2002
Medientyp:	academicJournal
Umfang:	print, 11 ref
ISSN:	0889-2229 (print)
Schlagwort:	Europe Est Eastern Europe Europa del Este Europe Europa Ukraine Ukrania Immunology, immunopathology, allergology Immunologie, immunopathologie, allergologie Microbiology, infectious diseases Microbiologie, maladies infectieuses Virology Virologie Sciences biologiques et medicales Biological and medical sciences Sciences medicales Medical sciences Pathologie infectieuse Infectious diseases Viroses Viral diseases Viroses humaines Human viral diseases Viroses du tissu lymphoïde et du sang. Sida Viral diseases of the lymphoid tissue and the blood. Aids Immunodéficit Immune deficiency Inmunodeficiencia Immunopathologie Immunopathology Inmunopatología Infection Infección Lentivirus Retroviridae Virose Viral disease Virosis Virus immunodéficience humaine Human immunodeficiency virus Virus Epidémiologie Epidemiology Epidemiología Génotype Genotype Genotipo Homme Human Hombre Isolat clinique Clinical isolate Aislado clinico SIDA AIDS Soustype Subtype Subtipo Toxicomanie Drug addiction Toxicomanía Virus HIV1 HIV-1 virus Voie intraveineuse Intravenous administration Vía intravenosa Subject Geographic: Europe Est Eastern Europe Europa del Este Europe Europa Ukraine Ukrania
Sonstiges:	Nachgewiesen in: PASCAL Archive Sprachen: English Original Material: INIST-CNRS Document Type: Article File Description: text Language: English Author Affiliations: Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, Netherlands ; Institute of Epidemiology and Infectious Diseases, Academy of Medical Sciences of Ukraine, 03038 Kiev, Ukraine ; D.I. Ivanovsky Institute of Virology, Russian Academy of Medical Sciences, 123098 Moscow, Russian Federation Rights: Copyright 2003 INIST-CNRS ; CC BY 4.0 ; Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS Notes: Infectious pathology

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